Services
Contractile Profiling
Are you hitting the right contractility mark?
Desirable biochemical effects do not assure beneficial pharmacology in the human heart. The complexity of the cardiac contractile apparatus often results in pharmacophores producing multiple simultaneous effects on muscle performance. Generating a complete and accurate picture of cardiac contractility in human tissues is essential for hitting the desired physiological mark.
Propria’s patent-pending technology provides:
- Direct measurement of contractile properties in human cardiac tissue
- Real-time monitoring of thin, diffusion-friendly cardiac tissues
- Detailed physiological relationships, including interplay between contraction and relaxation parameters
With applications for basic research and drug discovery, including:
- Disease modeling
- Hit identification and lead optimization support
Representative, relatively simple figure with brief description:
Comprehensive characterization of the contractile profile for human cardiac tissues provides an unparalleled ability to predict human physiology. Propria’s MyoLab system is used to capture the key functional parameters in mature human engineered heart tissues (hEHTs) efficiently and accurately.
Learn more about our Platform here.
Contractile Profiling
Are you hitting the right contractility mark?
Desirable biochemical effects do not assure beneficial pharmacology in the human heart. The complexity of the cardiac contractile apparatus often results in pharmacophores producing multiple simultaneous effects on muscle performance. Generating a complete and accurate picture of cardiac contractility in human tissues is essential for hitting the desired physiological mark.
Propria’s patent-pending technology provides:
- Direct measurement of contractile properties in human cardiac tissue
- Real-time monitoring of thin, diffusion-friendly cardiac tissues
- Detailed physiological relationships, including interplay between contraction and relaxation parameters
With applications for basic research and drug discovery, including:
- Disease modeling
- Hit identification and lead optimization support
Representative, relatively simple figure with brief description:
Comprehensive characterization of the contractile profile for human cardiac tissues provides an unparalleled ability to predict human physiology. Propria’s MyoLab system is used to capture the key functional parameters in mature human engineered heart tissues (hEHTs) efficiently and accurately.
Learn more about our Platform here.