News and Publications
Propria’s engineered heart tissue technology has contributed substantially to scientific presentations and peer-reviewed publications in recent years.
January 2024
Classifying pathogenicity of TPM1 variants of unknown significance using in vitro and in silico approaches
October 2023
Chronic diastolic stretch unmasks conduction defects in an in vitro model of arrhythmogenic cardiomyopathy
February 2023
Modeling Hypertrophic Cardiomyopathy Due to MYBPC3 Haploinsufficiency with Engineered Heart Tissues
January 2023
Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TPM1 variant S215L
September 2022
Physiological calcium combined with electrical pacing accelerates maturation of human engineered heart tissue
September 2021
Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation
November 2020