MyoPod™ Human Engineered Heart Tissues (hEHTs)

MyoPod™ Human Engineered Heart Tissues (hEHTs)

MyoPod hEHTs are fully functional, mature, and machine-readable human cardiac tissues.

Key advantages of MyoPod hEHTs

  • Created by seeding cells into decellularized myocardial matrix, enhancing cell alignment and maturity
  • Ribbon-like tissues are thin and accessible (oxygen diffusion, viral particles, traditional RNA approaches, etc.)
  • Designed for optimal mechanical measurements

 

Propria Beating Heart Tissue-1

Validation of MyoPod hEHT Performance

  • Excellent maturation profile relative to adult human tissue
04_comparison_to_adult_human_trabeculae
 
  • Realistic responses to common inotropes and inhibitors
05_drug_responses_single_EHTs
MyoPod-hEHTs

Scaffold design and advantages

Engineered with unrelenting attention to detail and quality control, our MyoPod™ scaffold system enables reliable production of robust, machine-readable tissues.

 

Scaffold

Provoke Phenotypes with MyoPod® Stretch

MyoPod® Stretch cassettes allow the introduction of a 20% chronic stretch after tissues are formed. Chronic stretch in culture can be used to study cardiomyocyte responses to increased mechanical load and can be useful in exposing disease phenotypes in mutant cell lines.

 

introducing_MyoPod_Stretch

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